Designing Clinical Research : an epidemiologic approach - Hulley, Stephen B; Cummings, Steven R; Browner, Warren S; Newman, Thomas B; Hearst, Norman (Baltimore : Williams & Wilkins, 1988)
Getting started: the anatomy and physiology of research -- Conceiving the research question -- Choosing the study subjects: specification and sampling -- Planning the measurements: precision and accuracy -- Planning the measurements: questionnaires -- Using secondary data -- Designing a new study: I. Cohort studies -- Designing a new study: II. Cross-sectional and case-control studies -- Designing a new study: III. Diagnostic tests -- Enhancing causal inference in observational studies -- Designing a new study: IV. Experiments -- Getting ready to estimate sample size: hypotheses and underlying principles -- Estimating sample size and power -- Addressing ethical issues -- Planning for data management and analysis -- Implementing the study: pretesting, quality control, and protocol revisions -- Writing and funding a research proprosal
Includes bibliographical references and index.
Keywords: Clinical trials -- Technique; Medicine -- Research -- Methodology; Biochemistry -- Research -- Methodology; Epidemiologic Methods; Research Design