TY  - BOOK
AU  - Hulley,Stephen B
AU  - Cummings,Steven R
AU  - Browner,Warren S
AU  - Newman,Thomas B
AU  - Hearst,Norman
TI  - Designing Clinical Research: an epidemiologic approach 
SN  - 0683042491 (pbk.)
U1  - 610.72 19
PY  - 1988///
CY  - Baltimore
PB  - Williams & Wilkins
KW  - Clinical trials
KW  - Technique
KW  - Medicine
KW  - Research
KW  - Methodology
KW  - Biochemistry
KW  - Epidemiologic Methods
KW  - Research Design
N1  - Includes bibliographical references and index; Getting started: the anatomy and physiology of research -- Conceiving the research question -- Choosing the study subjects: specification and sampling -- Planning the measurements: precision and accuracy -- Planning the measurements: questionnaires -- Using secondary data -- Designing a new study: I. Cohort studies -- Designing a new study: II. Cross-sectional and case-control studies -- Designing a new study: III. Diagnostic tests -- Enhancing causal inference in observational studies -- Designing a new study: IV. Experiments -- Getting ready to estimate sample size: hypotheses and underlying principles -- Estimating sample size and power -- Addressing ethical issues -- Planning for data management and analysis -- Implementing the study: pretesting, quality control, and protocol revisions -- Writing and funding a research proprosal
ER  -